Antiplatelet agents for the treatment and prevention of atherothrombosis

作者：Patrono Carlo^*; Andreotti Felicita; Arnesen Harald; Badimon Lina; Baigent Colin; Collet Jean Philippe; De Caterina Raffaele; Gulba Dietrich; Huber Kurt; Husted Steen; Kristensen Steen Dalby; Morais Joao; Neumann Franz Josef; Rasmussen Lars Hvilsted; Siegbahn Agneta; Steg Philippe Gabriel; Storey Robert F; Van de Werf Frans; Verheugt Freek

来源：European Heart Journal, 2011, 32(23): 2922-2933B.

DOI：10.1093/eurheartj/ehr373

• Atherothrombosis
• Antiplatelet drugs
• Aspirin
• Clopidogrel
• Dipyridamole
• Prasugrel
• Ticagrelor
• Ticlopidine

The clinical pharmacology of antiplatelet drugs has been reviewed previously by the European Society of Cardiology (ESC) Task force and by the 8th American College of Chest Physicians (ACCP) Evidence-Based Clinical Practice Guidelines. Moreover, information on the efficacy and safety of antiplatelet drugs in the treatment and prevention of atherothrombosis is provided by collaborative meta-analyses of 287 secondary prevention trials and 6 primary prevention trials. The present document intends to provide practicing physicians with an updated instrument to guide their choice of the most suitable antiplatelet strategy for the individual patient at risk, or with different clinical manifestations, of atherothrombosis.

• 出版日期2011-12