Association between a cardiovascular risk score and early markers of atherosclerotic disease in Chilean children

作者：Arnaiz Pilar; Pino Felipe; Marin Arnaldo; Barja Salesa; Aglony Marlene; Cassis Berta; Navarrete Carlos; Acevedo Monica^*

来源：Revista Medica de Chile, 2010, 138(10): 1226-1231.

• Atherosclerosis
• Cardiovascular diseases
• Childhood

Background: A cardiovascular risk score for children, that includes traditional risk factors, obesity, sedentary habits and a family history of cardiovascular disease, has been recently proposed by Spanish researchers. Aim: To apply this score in school age children in Santiago de Chile and correlate its results with markers of subclinical atherosclerotic disease. Material and Methods: Retrospective analysis of data obtained from 209 children, aged 11.5 +/- 2 years, studied between 2005 and 2006. Weight, height, blood pressure, ultrasound measurement of carotid intima-media thickness and flow mediated dilatation of brachial artery and ultrasensible C reactive protein (us PCR) were measured. The Spanish cardiovascular risk score was calculated and correlated with ultrasound parameters and C reactive protein. Results: According to the score, 173 children (83%) had a low cardiovascular risk, 28 (13%) an intermediate risk and 8 (4%) a high risk. There was no association between the cardiovascular risk score and carotid intima-media thickness, flow mediated arterial dilatation and us PCR. Conclusions: No significant association was observed between the proposed cardiovascular risk score and early markers of atherosclerotic disease in this group of children. (Rev Med Chile 2010; 138: 1226-1231).

• 出版日期2010-10