科研之友
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摘要
The synthesis of pyrano[3,4-b]indoles is described. The reaction sequence involves Sonogashira coupling of dihydropyran propargyl ether scaffolds with iodoanilines to afford intermediate indoles. Lewis acid-catalyzed Ionization of the dihydropyrans, followed by intramolecular C3 alkylation of the indole, provides the title compounds.
- 出版日期2011-8-5
