Unprecedented 1,3-Dipolar Cycloaddition: From 1,4,5,8-Naphthalene Bisimides to a New Heterocyclic Skeleton

作者：Gryko Daniel T^*; Rogacki Maciej K; Klajn Jan; Galezowski Michal; Stepien Dorota K; Cyranski Michal K

来源：Organic Letters, 2010, 12(9): 2020-2023.

DOI：10.1021/ol1005032

1,4,5,8-Naphthalene bisimides react as dipolarophiles with in situ formed azomethine ylides. Double 1,3-dipolar cycloaddition is followed by unique ring rearrangement and leads to the formation of two six-membered rings. The formation of hexacyclic products is rationalized based on DFT calculations.

• 出版日期2010-5-7