科研之友
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摘要
The tissue penetration limitation of excitation light and the absorption wavelength of the photosensitizer hinder the effective treatment of traditional photodynamic therapy (PDT) in deep-seated tumors. Recently, X-ray excited photodynamic therapy (XE-PDT) based on excitation or indirect excitation of photosensitizers via energy transfer by X-ray has attracted a great deal of attention. In this review, recent progress of nanoscintillators, including their rational designs, strategies of photosensitizer loading as well as effects of energy transfer and PDT are summarized The main problems, challenges and future development in deep-seated tumor PDT are also discussed.
- 出版日期2017-12
- 单位南京大学
