A total synthesis of sarcandralactone A: a general, concise, RCM enabled approach to lindenanolide sesquiterpenoids

作者：Ramesh Subburethinam; Mehta Goverdhan

来源：Tetrahedron Letters, 2015, 56(25): 3941-3944.

DOI：10.1016/j.tetlet.2015.04.132

• Sesquiterpenoid synthesis
• Lindenanolides
• RCM
• Simmons-Smith cyclopropanation
• Julia-Kocienski reaction

A total synthesis of lindenane-type sesquiterpenoid natural product sarcandralactone A and its close sibling 5-epi-shizukanolide has been accomplished through a concise strategy in which a one-pot gamma-lactone annulation and a RCM reaction constitute pivotal steps.

• 出版日期2015-6-17