ANTISTAPHYBASE: database of antimicrobial peptides (AMPs) and essential oils (EOs) against methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus aureus

作者：Zouhir Abdelmajid^*; Taieb Malek; Lamine Mohamed Ashraf; Cherif Ammar; Jridi Taoufik; Mahjoubi Basma; Mbarek Sarra; Fliss Ismail; Nefzi Adel; Sebei Khaled; Ben Hamida Jeannette

来源：Archives of Microbiology, 2017, 199(2): 215-222.

DOI：10.1007/s00203-016-1293-6

• Anti-MRSA peptides
• Anti-MRSA EOs
• Anti-S. aureus peptides
• Anti-S. aureus EOs

Staphylococcus aureus and methicillin-resistant S. aureus are major pathogens. The antimicrobial peptides and essential oils (EOs) display narrow- or broad-spectrum activity against bacteria including these strains. A centralized resource, such as a database, designed specifically for anti-S. aureus/anti-methicillin-resistant S. aureus antimicrobial peptides and EOs is therefore needed to facilitate the comprehensive investigation of their structure/activity associations and combinations. The database ANTISTAPHYBASE is created to facilitate access to important information on antimicrobial peptides and essential peptides against methicillin-resistant S. aureus and S. aureus. At the moment, the database contains 596 sequences of antimicrobial peptides produced by diverse organisms and 287 essential oil records. It permits a quick and easy search of peptides based on their activity as well as their general, physicochemical properties and literature data. These data are very useful to perform further bioinformatic or chemometric analysis and would certainly be useful for the development of new drugs for medical use. The ANTISTAPHYBASE database is freely available at: https://www.antistaphybase.com/.

• 出版日期2017-3