Asynchronous Response of Coupled Pacemaker Neurons

作者:Dodla Ramana*; Wilson Charles J
来源:Physical Review Letters, 2009, 102(6): 068102.
DOI:10.1103/PhysRevLett.102.068102

摘要

We study a network model of two conductance-based pacemaker neurons of differing natural frequency, coupled with either mutual excitation or inhibition, and receiving shared random inhibitory synaptic input. The networks may phase lock spike to spike for strong mutual coupling. But the shared input can desynchronize the locked spike pairs by selectively eliminating the lagging spike or modulating its timing with respect to the leading spike depending on their separation time Such loss of synchrony is also found in a large network of sparsely coupled heterogeneous spiking neurons receiving shared input.

  • 出版日期2009-2-13