Accuracy of automatic detection of small-bowel mucosa by second-generation colon capsule endoscopy

作者：Adler Samuel; Hassan Cesare^*; Metzger Yoav; Sompolinsky Yishai; Spada Cristiano

来源：Gastrointestinal Endoscopy, 2012, 76(6): 1170-1174.

DOI：10.1016/j.gie.2012.07.034

Background: Colon capsule endoscopy (CCE) is a noninvasive technique for the detection of colorectal lesions. However, for CCE to be offered as an out-of-clinic procedure, the system needs to automatically alert the patient when to ingest the laxative (booster). %26lt;br%26gt;Objective: We tested the reliability of the automatic detection of the small-bowel (SB) mucosa and the subsequent alert for booster ingestion by the Data Recorder 3 (DR3) of the second-generation CCE (CCE-2). %26lt;br%26gt;Design and Setting: Retrospective analysis. %26lt;br%26gt;Patients and Intervention: Data from 120 consecutive cases of CCE-2 were analyzed for proper DR3 automatic detection of the capsule entering the SB to prompt the patient to ingest the laxative booster. %26lt;br%26gt;Main Outcome Measurements: Accuracy of the DR3 for detecting the SB mucosa. %26lt;br%26gt;Results: The DR3 correctly identified the proper time for ingestion of the laxative (booster) in 118 of 120 cases, corresponding to a sensitivity of 98.3% (95% CI, 97%-100%). The median time difference between DR3 automatic SB detection to the observed entrance of the capsule into the SB was 3 minutes 30 seconds (interquartile range 2 minutes 35 seconds to 5 minutes 57 seconds). %26lt;br%26gt;Limitation: Retrospective analysis. %26lt;br%26gt;Conclusions: The 98.3% sensitivity of the DR3 for automatic identification of the SB mucosa and subsequent alert for the first laxative (booster) ingestion paves the way for CCE-2 to be offered as an out-of-clinic procedure. (Gastrointest Endosc 2012;76:1170-4.)

• 出版日期2012-12