Ultrasound promoted selective synthesis of 2-aryl-5,6-dihydro-4H-1,3-oxazines catalyzed by K-10 and KSF montmorillonite clays: A practical procedure under mild and solvent-free conditions

作者：Mohammadpoor Baltork Iraj^*; Moghadam Majid; Tangestaninejad Shahram; Mirkhani Valiollah; Eskandari Zohre

来源：Ultrasonics Sonochemistry, 2010, 17(5): 857-862.

DOI：10.1016/j.ultsonch.2010.02.005

• Oxazines
• Ultrasonic irradiation
• Solvent-free
• Montmorillonite
• Heterogeneous catalyst

Montmorillonite K-10 and KSF were found to be highly efficient, environmentally friendly and recyclable heterogeneous catalysts for the selective synthesis of a variety of 2-aryl-5,6-dihydro-4H-1,3-oxazines from arylnitriles and 3-amino-1-propanol under ultrasound irradiation. This new methodology provides excellent yields in short reaction times (10-25 min). The reaction work-up is very simple and the catalysts can be easily separated from the reaction mixture and reused several times in subsequent reactions. This catalytic system also exhibits excellent chemoselectivity in the synthesis of mono-oxazines from dinitriles.

• 出版日期2010-6