A Novel Hybrid Metal-Organic Framework-Polymeric Monolith for Solid-Phase Microextraction

作者：Lin Chen Lan; Lirio Stephen; Chen Ya Ting; Lin Chia Her; Huang Hsi Ya

来源：Chemistry - A European Journal, 2014, 20(12): 3317-3321.

DOI：10.1002/chem.201304458

• capillary electrochromatography
• metal-organic frameworks
• penicillin
• polymers
• solid-phase microextraction

This study describes the fabrication of a novel hybrid metal-organic framework- organic polymer (MOF-polymer) for use as a stationary phase in fritless solid-phase microextraction (SPME) for validating analytical methods. The MOF-polymer was prepared by using ethylene dimethacrylate (EDMA), butyl methacrylate (BMA), and an imidazolium-based ionic liquid as porogenic solvent followed by microwave-assisted polymerization with the addition of 25% MOF. This novel hybrid MOF-polymer was used to extract penicillin (penicillin G, penicillin V, oxacillin, cloxacillin, nafcillin, dicloxacillin) under different conditions. Quantitative analysis of the extracted penicillin samples using the MOF-organic polymer for SPME was conducted by using capillary electrochromatography (CEC) coupled with UV analysis. The penicillin recovery was 63-96.2% with high reproducibility, sensitivity, and reusability. The extraction time with the proposed fabricated SPME was only 34 min.

• 出版日期2014-3-17