A new cytotoxic flavonoid from the fruit of Sinopodophyllum hexandrum

作者：Kong Yue; Xiao Jun Jun; Meng Shu Cong; Dong Xiao Min; Ge Yue Wei; Wang Ru Feng; Shang Ming Ying^*; Cai Shao Qing

来源：Fitoterapia, 2010, 81(5): 367-370.

DOI：10.1016/j.fitote.2009.11.003

• 8,2'-diprenylquercetin 3-methyl ether
• Sinopodophylli Fructus
• Sinopodophyllum hexandrum
• Cytotoxic activity

Constituents of the fruit of Sinopodophyllum hexandrum (Royle) Ying (Sinopodophylli Fructus) were investigated. A new flavonoid, 8,2'-diprenylquercetin 3-methyl ether along with 9 known compounds were isolated and identified. Among them, the new compound 8,2'-diprenylquercetin 3-methyl ether exhibited cytotoxic activities against MDA-231 and T47D breast cancer cell lines, quercetin, kaempferol and rutin were isolated from Sinopodophylli Fructus for the first time.

• 出版日期2010-7
• 单位北京大学