Antibacterial activity of Citrus limonum fruit juice extract

作者：Okeke Malachy Ifeanyi^*; Okoli Arinze Stanley; Eze Edith Nneka; Ekwutme Grace Chinwe; Okosa Evangelin Uchena; Iroegbu Christian Ukvvuoma

来源：Pakistan Journal of Pharmaceutical Sciences, 2015, 28(5): 1567-1571.

• Antibacterial
• lemon juice
• Citrus limonum
• enthomedicine
• Nigeria

The fruit juice extract of Citrus limonum was investigated for antibacterial activity. The antibacterial activity of the extract on ten strains of bacteria was determined by both agar well diffusion and macro-broth dilution methods. The extract was variously bacteriostatic and bactericidal against Bacillussubtilis ATCC 6051, Staphylococcus aureus ATCC 12600, Escherichia coli ATCC 11775, Pseudomonas aeruginosa ATCC 10145 as well as locally isolated clinical strains of the above bacteria and Salmonella kintambo (Human: 13, 23: mt:-), Salmonella typhi and Proteus sp. The MICs ranged from 0.78mg/ml to 50mg/ml; MBCs, 25.0mg/ml to >100mg/ml and MBC/MIC ratios 2.0 to >16.0. These results provide scientific justification for the medicinal use of Citrus limonum fruit juice by Nigerian herbalists in the treatment of diseases in which strains of the test organisms have been implicated as etiologic agents.

• 出版日期2015-9
• 单位河北医科大学