A Study of Two Highly Active, Air-Stable Iron(III)-mu-Oxo Precatalysts: Synthetic Scope of Hydrophosphination using Phenyl- and Diphenylphosphine

作者：Gallagher Kimberley J; Espinal Viguri Maialen; Mahon Mary F^*; Webster Ruth L^*

来源：Advanced Synthesis & Catalysis, 2016, 358(15): 2460-2468.

DOI：10.1002/adsc.201501179

• homogeneous catalysis
• iron
• phosphines
• porphyrins
• Schiff bases

The importance of phosphines in synthetic chemistry cannot be underestimated. Catalytic hydrophosphination offers an ideal method to prepare P-C bonds without the need for harsh reaction conditions or stoichiometric amounts of waste by-product. We herein report our studies into two biocompatible iron(III) complexes in hydrophosphination chemistry using diphenylphosphine under mild and benign reaction conditions (room temperature, sol-vent-free) and our extended exploration of hydrophosphination with phenylphosphine, which can be tuned to operate in the absence of catalyst under thermal conditions for single hydrophosphination or solvent-free with an iron(III) precatalyst to generate the products of double hydrophosphination.

• 出版日期2016-7-28