Farinamycin, a Quinazoline from Streptomyces griseus

作者:Nett Markus*; Hertweck Christian
来源:Journal of Natural Products, 2011, 74(10): 2265-2268.
DOI:10.1021/np2002513

摘要

The metabolic potential of a Streptomyces griseus strain was investigated under various cultivation conditions. After fermentation in a flour-based medium, a new quinazoline metabolite, farinamycin (1), could be isolated from the bacterium, which was previously known only for the production of phenoxazinone antibiotics. The structure of 1 illuminates the biosynthetic versatility of S. griseus, which assembles a defined set of building blocks into structurally diverse natural products.

  • 出版日期2011-10