A STUDY ON THE INHIBITORY EFFECT OF MATRINE ON GASTRIC CANCER SGC-7901 CELLS

作者：Song, Shimao^*; Zhu, Shengming; Zhang, Zhiguo; Mo, Zhengying; Ke, Qing; Luo, Zhiguo

来源：African Journal of Traditional, Complementary and Alternative Medicines, 2013, 10(6): 435-438.

DOI：10.4314/ajtcam.v10i6.5

• Matrine
• SGC-7901
• MTT assay

The objective of this paper was to investigate the antitumour mechanism of action of matrine by studying its inhibitory effect on gastric cancer SGC-7901 cells. SGC-7901 cells were chosen, and cell-killing capacity of matrine on gastric cancer SGC-7901 cells was determined using MTT assay and single PI staining assay. The results showed that matrine had an inhibitory effect on gastric cancer SGC-7901 cells, which was somewhat dose-dependent. The study concluded that matrine has a significant in-vitro inhibitory effect on SGC-7901 tumour cells, influences cell cycle of SGC-7901 cells, and induces their apoptosis.

• 出版日期2013
• 单位湖北医药学院