An alternative treatment option in tubal ectopic pregnancies with fetal heartbeat: aspiration of the embryo followed by single-dose methotrexate administration

作者：Cepni Ismail; Guralp Onur^*; Ocal Pelin; Salahov Ramin; Gurleyen Hazel; Idil Mehmet

来源：Fertility and Sterility, 2011, 96(1): 79-83.

DOI：10.1016/j.fertnstert.2011.02.058

• Fetus aspiration
• living
• methotrexate
• ossification
• tubal ectopic pregnancy
• unruptured

Objective: To present 13 cases of unruptured tubal ectopic pregnancies successfully treated with ultrasound-guided aspiration and local and systemic methotrexate (MTX) administration.
Design: Case series.
Setting: University hospital.
Patient(s): Thirteen women with an unruptured tubal ectopic pregnancy.
Intervention(s): Transvaginal ultrasound-guided aspiration of the tubal ectopic pregnancy followed by MTX administration into the gestational sac (half of the calculated total dose of 25 mg/m(2)) and intramuscular injection (the remaining half of the calculated total dose of 25 mg/m(2)).
Main Outcome Measure(s): Recovery of the patients, successful conservative treatment of the tubal ectopic pregnancies with preservation of the fallopian tubes.
Result(s): Twelve (92%) of 13 women were successfully aborted, without need for salpingectomy or salpingostomy.
Conclusion(s): Transvaginal ultrasound-guided aspiration of fetus followed by local and systemic methotrexate administration can be safely used to treat unruptured tubal ectopic pregnancies. (Fertil Steril (R) 2011;96:79-83.

• 出版日期2011-7