Advantageous Use of (Bu2P)-Bu-t-N=P((BuNCH2CH2)-Bu-i)(3)N in the Hiyama Coupling of Aryl Bromides and Chlorides

作者：Raders Steven M; Kingston Jesudoss V; Verkade John G^*

来源：Journal of Organic Chemistry, 2010, 75(5): 1744-1747.

DOI：10.1021/jo902338w

An efficient catalytic route to biaryls by employing (generally) only 0.25 mol % of Pd(OAc)(2) and 0.5 mol % of 1 in the Hiyama coupling reaction is reported. High yields for electron-rich, -neutral, and -deficient aryl chlorides are obtained. A variety of phenylsiloxanes undergo coupling with aryl bromides and chlorides with low Pd(OAc)(2)/1 loadings.

• 出版日期2010-3-5