Alveolar soft part sarcoma with multiple brain and lung metastases in pregnancy A case report and literature review

作者：Wang Yubo; Cui Jiayue; Yan Xu; Jin Rihua; Hong Xinyu^*

来源：Medicine, 2017, 96(46): e8790.

DOI：10.1097/MD.0000000000008790

• alveolar soft part sarcoma
• brain metastases
• brain neoplasms
• pregnant women

Rational: Alveolar soft part sarcomas (ASPSs) with multiple brain metastases in pregnancy is a rare entity.
Patient concerns: We report our experience with a 19-year-old pregnant woman who presented with intermittent headaches and vomiting at 38 weeks gestation.
Diagnoses: The patient was initially diagnosed as brain metastasis according to computed tomography and magnetic resonance imaging (MRI) imaging.
Interventions: Cesarean section and craniotomy (complete resection of both brain metastatic lesions) was performed sequentially.
Outcomes: A healthy baby girl was delivered safely and no neonatal malformations were found. Histological analysis confirmed the diagnosis of ASPS. Follow-up MRI performed 10 months after surgery revealed no residual tumor or signs of recurrence.
Lessons: We report a case of ASPS with multiple brain and lung metastases in a pregnant woman. We recommend timely MRI examination for diagnosis and have discussed the approach to the treatment of pregnant women with brain metastasis.

• 出版日期2017-11
• 单位吉林大学