Asymmetric transfer hydrogenation reaction in water: Comparison of chiral proline amide/amine ruthenium(II) complexes

作者：Denizalti Serpil^*; Mercan Deniz; Sen Betul; Gokce Aytac Gurhan; Cetinkaya Bekir

来源：Journal of Organometallic Chemistry, 2015, 779: 62-66.

DOI：10.1016/j.jorganchem.2014.12.023

• L-proline
• Ruthenium
• Asymmetric transfer hydrogenation

Chiral proline amide/amine ligands (2, 3), synthesized by multi-step reaction starting from L-proline (1), were evaluated as catalyst generated in situ from [RuCl2(p-cymene)](2) for asymmetric transfer hydrogenation of aromatic ketones in the presence of sodium formiate and sodium dodecyl sulfate (SDS). The results revealed that efficiencies and enantioselectivities strongly depend on the N-substituents.

• 出版日期2015-3-1