Novel and Highly Effective Method for the Trimethylsilylation of Alcohols and Phenols with Hexamethyldisilazane (HMDS), Catalyzed by I-2 Generated in situ Using Fe(NO3)(3)center dot 9H(2)O/NaI under Heterogeneous and Neutral Conditions

作者：Khazaei Ardeshir^*; Rahmati Sadegh; Rostami Amin

来源：Helvetica Chimica Acta, 2009, 92(7): 1434-1438.

Structurally diverse alcohols and phenols were trimethylsilylated in a clean and efficient reaction with hexamethyldisilazane (HMDS) based on the use of I-2 generated in situ from Fe(NO3)(3)center dot 9H(2)O/NaI. The reaction occurs very rapid in good-to-high yield in CH2Cl2 at room temperature, and the use of toxic and corrosive molecular I-2 is avoided.

• 出版日期2009