A Quinazolinone based fluorescent chemosensor for selective detection of Fe(III) in aqueous media: Applications to pharmaceutical and environmental analysis

作者：Dongare Pravin R; Gore Anil H; Kondekar Uttam R; Kolekar Govind B; Ajalkar Balu D

来源：Inorganic and Nano-Metal Chemistry, 2018, 48(1): 49-56.

DOI：10.1080/24701556.2017.1357631

• Quinazolinone
• Fluorescent chemosensor
• Fe3+ ion
• Aqueous media
• DFT

A Quinazolinone based chemosensor 2-(1,3-thiazol-2-yl)-2,3-dihydroquinazolin-4(1 H)-one (1) has been synthesized, that exhibits high sensitivity and selectivity for Fe3+ over other environmentally and biologically relevant metal ions by the changes in fluorescence properties and reversible with the addition of EDTA. Under the optimized conditions, Stern-Volmer plot gives a good relationship between chemosensor 1 and Fe3+ with detection limit 0.0366 mu g.mL(-1). The binding mode of 1 toward Fe3+ has been investigated by Job's plot, Benesi-Hildebrand plot, FTIR spectra measurements and theoretically supported by DFT calculations. Moreover, the sensor was successfully 'applied for quantitative determination of Fe3+ ions in pharmaceutical and water sample.

• 出版日期2018