An inverse relation between the Simplified Menopausal Index and biological antioxidant potential

作者：Chen J T^*; Kotani K

来源：Climacteric, 2013, 16(2): 288-291.

DOI：10.3109/13697137.2012.696291

• OXIDATIVE STRESS
• BAP TEST
• ANTIOXIDANT CAPACITY
• MENOPAUSAL INDEX

Background Inasmuch as female sex hormones can exhibit antioxidative activity, the oxidative-antioxidative imbalance is mechanistically postulated to be involved in menopausal symptoms. %26lt;br%26gt;Objectives The objectives of this study were to investigate the correlation between the established menopausal index and blood levels of the in vivo antioxidative potential in women. %26lt;br%26gt;Method Blood antioxidant levels were examined by the biological antioxidative potential (BAP) test and menopausal-like symptoms were determined using the Simplified Menopausal Index (SMI) in 160 healthy Japanese women (mean age 52 years). %26lt;br%26gt;Results A correlation analysis revealed a significant inverse relationship between the BAP and SMI levels, independent of age and the body mass index. %26lt;br%26gt;Conclusions The data suggest that menopausal symptoms may be associated with a decrease in antioxidant potential as assessed by the BAP test.

• 出版日期2013-4