Nucleophilic Functionalizations of Aniline Derivatives: Aromatic Pummerer Reaction for Umpolung Halogenation and Hydroxylation on Benzene Ring

作者：Bao, Xingping; Yao, Jinzhong; Zhou, Hongwei^*; Xu, Guangyu^*

来源：Organic Letters, 2017, 19(21): 5780-5782.

DOI：10.1021/acs.orglett.7b02720

• PROPARGYL-ALLENYL ISOMERIZATIONS
• ARYL SULFOXIDES
• ACETIC-ACID
• POLYFUNCTIONALIZED BENZENES
• SEQUENTIAL REACTIONS
• EFFICIENT SYNTHESIS
• 4+2 CYCLOADDITION
• SULFUR
• SULFIDES
• DESULFURIZATION

In this paper, a metal-free protocol of nucleophilic ortho-halogenation and hydroxylation of anilines via an aromatic Pummerer process is reported.

• 出版日期2017-11-3
• 单位嘉兴学院; 湖南师范大学