科研之友
微信
新浪微博
Facebook
分享链接
摘要
Anionic annulation of appropriate 2,3-disubstituted pyrroles with Michael acceptors provides an expedient route to densely substituted 7-hydroxyindoles. Intrinsic to the methodology, the resulting substituents are disposed in a fully regiocontrolled manner. The methodology is applicable to the synthesis of 7-hydroxybenzofurans. None of the indoles/benzofurans or pyrrole synthons synthesized in this study have hitherto been reported.
- 出版日期2014-9
