A correlation analysis on multiplex three-dimensional brain gene expression mapping of Parkinson disease

作者：Liu Qiang^*; Li Haiyun

来源：IEEE/ICME International Conference on Complex Medical Engineering, 2007-05-23 to 2007-05-27.

DOI：10.1109/ICCME.2007.4382015

• PD
• correlation coefficient
• classification
• hierarchical cluster analysis

This paper is aimed to predict Parkinson disease (PD) genes from multiplex Three-Dimensional brain gene expression mapping. First, we select the available data from the original datasets and use log ratio as the object that we would analysis. Second, correlation coefficient calculated provides information on the correlation between genes based on gene expression levels. Later, classification and hierarchical cluster analysis can help us to find the relevant genes of Parkinson disease. The 27 genes selected by the statistical method are worthy of further experiments to assess the results of microarray.

• 出版日期2007
• 单位首都医科大学