A novel mechanism of preconditioning:Attenuating reperfusion injury through enhanced myocardial glucose uptake via insulin-stimulated Akt and AMPK activation

作者：季乐乐; Haifeng Zhang; Feng Gao

来源：中国生理学会.

• AMPK
• IPC
• GLUT
• Akt

<正>Aims:Ischemic preconditioning(IPC)is an intrinsic protective mechanism which markedly enhanced the ability of the heart to withstand a subsequent ischemic injury.We previously found that IPC cardioprotection was markedly attenuated in diabetic rats.Therefore,we hypothesized that insulin-regulated...

• 出版日期2013
• 单位第四军医大学