A close correlation between plasma and serum levels of brain-derived neurotrophic factor (BDNF) in healthy volunteers

作者：Yoshimura Reiji^*; Sugita Ikenouchi Atsuko; Hori Hikaru; Umene Nakano Wakako; Hayashi Kenji; Katsuki Asuka; Ueda Nobuhisa; Nakamura Jun

来源：International Journal of Psychiatry in Clinical Practice, 2010, 14(3): 220-222.

DOI：10.3109/13651501003748560

• Brain-derived neurotrophic factor
• plasma
• serum

Objective. Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophic family found in both the central and the peripheral nervous system. Blood BDNF levels are considered as a state marker for depression. Methods. We investigated serum and plasma levels of BDNF levels in 103 healthy volunteers (M/F: 39/64, age: 37 +/- 12 years) using ELISA methods. Results and Conclusions. Serum BDNF levels were 14-fold higher than plasma BDNF levels, and a close relationship was found between serum and plasma BDNF levels.

• 出版日期2010-9