Adulticidal Efficacy of a Formulation of Fipronil/(S)-methoprene/cyphenothrin Against KS1 (Kansas State 1) Ctenocephalides felis felis (Bouche) Fleas

作者：Dryden Michael^*; Carithers Doug; Solanki Ruchika; Gross Sheila J

来源：International Journal of Applied Research in Veterinary Medicine, 2016, 14(3): 203-207.

• Ctenocephalides felis felis
• Cat flea
• Dogs
• Efficacy
• Flea control
• Fleas
• KS1 flea strain

Background
A study was conducted to evaluate the efficacy of FRONTLINE (R) TRITAK (R) For Dogs (fipronil/(S)-methoprene/cyphenothrin, Merial, Inc., Duluth, GA) against a known strain of fleas with a history of reduced susceptibility to fipronil and pyrethroids, KS1 (Kansas State 1), of Ctenocephalides felis felis fleas.
Methods
One day after topical treatment with placebo or active, dogs (n = 32) were infested with 100 unfed adult KS1 fleas, with repeat infestations on Days 7, 14, 2,1 and 28. The number of live fleas was counted at 12 hours post-infestation for Groups 1 (n=8) and 3 (n=8) and at 24 hours post-infestation for Groups 2 (n=8) and 4 (n=8).
Results
Observed efficacies were 97.1-99.8% at 12-hour assessments on Day 1 through Day 28 and 99.8-100% at 24-hour assessments, occurring on Day 2 through Day 29.
Conclusions
A single dose of FRONTLINE (R) TRITAK (R) For Dogs (fipronil/(S)-methoprene/cyphenothrin) (0.67 ml or 1.34 ml) provided excellent efficacy against the KS1 Ctenocephalides felis felis flea strain for up to 4 weeks after treatment.

• 出版日期2016