Dual-sugar Nanogel Comprising beta-1,3-Glucan and Cholesterol-bearing Dextran for Protein Delivery Targeting Antigen Presenting Cells

作者：Maegawa Yoshiya; Mochizuki Shinichi; Sanada Yusuke; Akiyoshi Kazunari; Sakurai Kazuo^*

来源：Chemistry Letters, 2014, 43(5): 652-654.

DOI：10.1246/cl.131201

A dual-sugar nanogel containing proteins was prepared by a simple mixing of schizophyllan (SPG) in NaOH (0.25 M), cholesterol-hydrophobized dextran (CH-CDex) in NaH2PO4 solution, and BSA. It was found that this nanogel was specifically taken up by SPG receptors present on antigen presenting cells.

• 出版日期2014-5-5