A random, case-control study on the efficacy and safety of Weishi Bitong Xifang fumigation for mild and moderate knee osteoarthritis patients

作者：Zhang, Hao; Liu, Tao; Li, Feiyue^*

来源：International Journal of Rheumatic Diseases, 2015, 18(5): 502-507.

DOI：10.1111/1756-185X.12165

• visual analogue scale
• Weishi Bitong Xifang fumigation
• Western Ontario and McMaster Universities Osteoarthritis Index

ObjectiveTo explore the efficacy and safety of Weishi Bitong Xifang fumigation for treating patients with knee osteoarthritis (KOA). @@@ MethodsA total of 100 KOA patients were randomly assigned to receive Weishi Bitong Xifang fumigation and washing (fumigation group, n=50) or unctions of votalin emulgel (Voltaren emulgel group, n=50) by means of a computer-generated random-number table. All the patients received two courses of therapy (2weeks per course). Visual analogue scale (VAS) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) were used to assess the curative effect. @@@ ResultsVisual analogue scale and WOMAC scores were significantly improved in both groups after treatment. However, VAS, stiffness and functional scores in the fumigation group were significantly lower than those in the Voltaren emulgel group after 4weeks of treatment. In addition, the occurrence rate of adverse effects in the fumigation group was also lower than that of the Voltaren emulgel group. @@@ ConclusionWeishi Bitong Xifang fumigation is an effective and safe method for treating KOA patients and should be widely applied in clinics.

• 出版日期2015-6
• 单位上海市闵行区中心医院; 上海交通大学