A Metal-Free Cross-Dehydrogenative Coupling Reaction of Amides to Access N-Alkylazoles

作者:Zhu, Zheng; Wang, Yufeng; Yang, Mingmeng; Huang, Ling; Gong, Jiuhan; Guo, Shengmei*; Cai, Hu*
来源:Synlett, 2016, 27(19): 2705-2708.
DOI:10.1055/s-0036-1588307

摘要

An iodine-catalyzed cross-dehydrogenative coupling reaction of N-alkyl amides and azoles is reported. The catalytic system provides an efficient method for introducing amides onto azoles, especially onto benzotriazoles.