A one-pot synthesis of trichloromethylated pyrimidines from trichloroacetimidamides and acetylenic esters

作者：Yavari Issa^*; Malekafzali Alaleh; Eivazzadeh Keihan Reza; Skoulika Stavroula; Alivaisi Rahman

来源：Tetrahedron Letters, 2016, 57(16): 1733-1735.

DOI：10.1016/j.tetlet.2015.12.066

• Pyrimidine
• Trichloroacetonitrile
• Tetramethylguanidine
• Acetylenic ester

A one-pot synthesis of functionalized trichloromethylated pyrimidines from the reaction of trichloroacetimidamides, generated by the addition of guanidine derivatives to trichloroacetonitrile, and acetylenic esters, in good yields is described.

• 出版日期2016-4-20