Antimicrobial delivery by intrasynovial catheterisation with systemic administration for equine synovial trauma and sepsis

作者：Stewart A A^*; Goodrich L R; Byron C R; Evans R B; Stewart M C

来源：Australian Veterinary Journal, 2010, 88(4): 115-123.

DOI：10.1111/j.1751-0813.2010.00553.x

• horses
• intrasynovial catheter
• synovial sepsis

Objective
To present the technique for intra-articular catheter placement and report the clinical outcomes of 38 cases of equine synovial trauma and/or infection treated with broad-spectrum antimicrobials administered via an intrasynovial catheter (ISC).
Design
Retrospective study.
Procedure
Medical records of 38 horses treated for synovial trauma and sepsis with frequent antimicrobial administration through an ISC from 1995 to 2008 were reviewed. Follow-up information was obtained via clinical re-evaluation or telephone contact with the owners.
Results
The majority of horses (84%) received amikacin and Timentin (R) four times daily. In addition, synovial lavage through the ISC was carried out in 27 horses (71%). Only radiological evidence of osteolysis had a significant negative impact on both lameness at the time of hospital discharge and the long-term outcome. In total, 92% of horses treated with frequent antimicrobial administration through an ISC had clinical resolution of infection. Catheter obstruction occurred in three cases, necessitating replacement or removal, and two synovial fistulae developed at sites of open drainage. The majority of horses treated had a favourable outcome, with 86% being at least pasture sound and 43% returned to riding.
Conclusion
Septic synovial structures treated with frequent antimicrobial administration through an ISC had a good prognosis for survival and 43% returned to riding, which is consistent with the results of other studies. The use of a simple ISC should be considered when broad-spectrum intrasynovial antimicrobial administration and lavage of a septic synovial structure are indicated.

• 出版日期2010-4