Assessment of nasal mucociliary activity in patients with Behcet's disease

作者：Ozbay I^*; Kucur C; Temizturk F; Ozkan Y; Kahraman C; Oghan F

来源：Journal of Laryngology and Otology, 2016, 130(4): 348-351.

DOI：10.1017/S0022215116000207

• Nasal Mucosa
• Behcet Disease
• Saccharin

Objective: To investigate nasal mucociliary clearance in patients with Behcet's disease.
Methods: Thirty patients with Behcet's disease, diagnosed on the basis of criteria defined by the International Study Group for Behcet's Disease, and 30 healthy individuals were recruited. In both groups, individuals with conditions that could affect nasal mucociliary clearance were excluded. Nasal mucociliary clearance time was evaluated using saccharin tests. The time between placement of a saccharin tablet and the tasting of the saccharin was measured and recorded as the saccharin clearance time.
Results: The mean nasal mucociliary clearance time was significantly longer in the Behcet's disease patients than in the control subjects (p < 0.001). Furthermore, there was a positive correlation between Behcet's disease duration and nasal mucociliary clearance time (p < 0.001, r = 0.882).
Conclusion: The results suggest that nasal mucociliary clearance time is longer in Behcet's disease patients than in control subjects, and is positively correlated with disease duration.

• 出版日期2016-4