A New Cytotoxic 19-Nor-cardenolide from the Latex of Antiaris toxicaria

作者：Dai, Hao-Fu; Gan, Yu-Juan; Que, Dong-Mei; Wu, Jiao; Wen, Zhen-Chang; Mei, Wen-Li^*

来源：Molecules, 2009, 14(9): 3694-3699.

DOI：10.3390/molecules14093694

• Antiaris toxicaria
• toxicarioside H
• nor-cardenolide
• cytotoxicity

A new nor-cardenolide, named toxicarioside H (1), was isolated from the latex of Antiaris toxicaria (Pers.) Lesch (Moraceae). Its structure was elucidated on the basis of HRFAB-MS and spectroscopic techniques (IR, UV, 1D and 2D NMR). Compound 1 showed significant cytotoxicity against K562, SGC-7901, SMMC-7721, and HeLa cell lines in vitro by MTT method.

• 出版日期2009-9
• 单位中国热带农业科学院; 海南大学