Disinfection of meticillin-resistant Staphylococcus aureus and Staphylococcus epidermidis biofilms using a remote non-thermal gas plasma

作者：Cotter J J; Maguire P; Soberon F; Daniels S; O'Gara J P; Casey E^*

来源：Journal of Hospital Infection, 2011, 78(3): 204-207.

DOI：10.1016/j.jhin.2011.03.019

• Biofilm
• Disinfection
• Gas plasma
• Meticillin-resistant Staphylococcus aureus Staphylococcus epidermidis

The effective disinfection of hospital surfaces is recognised as an important factor in preventing hospital-acquired infections. The purpose of this study was to quantify the disinfection rate of a novel gas plasma system on clinically relevant biofilms. Clinical isolates of Staphylococcus epidermidis and meticillin-resistant Staphylococcus aureus (MRSA) were grown as biofilms on glass surfaces and tested in a disinfection container remote from the plasma source. The strains used in this study were known to produce substantial quantities of biofilm and average log(10) counts were 9.0 and 9.1 cfu/cm(2) for S. epidermidis and MRSA respectively. Counts were reduced by between 4 and 4.5 log(10) after 1 h of exposure for MRSA and S. epidermidis respectively. More prolonged treatment in the case of MRSA biofilms resulted in a 5.5 log(10) reduction after 90 min. Biofilm samples were also placed in medical device packaging bags and similar rates of disinfection were observed.

• 出版日期2011-7