A sensitive colorimetric strategy for monitoring cerebral β-amyloid peptides in AD based on dual-functionalized gold nanoplasmonic particles

作者：Yu, Yan-yan; Zhang, Lin; Sun, Xiao-yu; Li, Cheng-lin; Qiu, Yu; Sun, Hao-peng; Tang, Dao-quan; Liu, Yao-wu; Yin, Xiao-xing^*

来源：Chemical communications, 2015, 51(42): 8880-8883.

DOI：10.1039/c5cc01855b

• SURFACE-PLASMON RESONANCE
• ALZHEIMERS-DISEASE
• BINDING-SITE
• COPPER
• NANOPARTICLES
• AGGREGATION
• IMMUNOASSAY
• PROTEIN
• BRAIN
• FLUID

A sensitive and selective strategy for the colorimetric visualization of the total monomeric Ab down to 40 pg mL(-1) based on dual-functionalized gold nanoplasmonic particles (GNPs) is developed and applied to evaluate Ab levels in the AD cerebral system.

• 单位
  徐州医科大学; 中国药科大学