Neonatal herpes simplex encephalitis: clinical profile versus molecular biology

作者:Izquierdo Giannina*; Cofre Jose; Pablo Torres J; Venegas Gerardo; Vergara Alejandra; Farfan Mauricio
来源:Revista Chilena de Infectologia, 2012, 29(4): 464-467.
DOI:10.4067/S0716-10182012000400019

摘要

Herpes simplex encephalitis is a diagnostic challenge and causes high morbidity and mortality in children. Early suspicion of the disease and a rapid, safe and useful diagnostic test are relevant because up to 70% of the cases may die. We report the case of a newborn girl aged 25 days, who presented with a clinical picture that was compatible with herpes simplex encephalitis where the confirmation of the etiological diagnosis was delayed. Only by repeated real-time polymerase chain reaction it was possible to confirm the presence of herpes simplex virus type 1 in the cerebrospinal fluid.

  • 出版日期2012-8

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