Dehydration of Aldoximes Using PhSe(O)OH as the Pre-Catalyst in Air

作者：Zhang, Xu; Sun, Jingjing; Ding, Yuanhua; Yu, Lei^*

来源：Organic Letters, 2015, 17(23): 5840-5842.

DOI：10.1021/acs.orglett.5b03011

• BAEYER-VILLIGER OXIDATION
• ORGANOSELENIUM COMPOUNDS
• HYDROGEN-PEROXIDE
• SELENIUM
• AMINATION
• ALKENES
• ACCESS
• DIHYDROXYLATION
• CYCLOHEXENE
• CYCLIZATION

PhSe(O)OH was found to be a good pre-catalyst for aldoxime dehydrations in open air. Compared with the previously reported (PhSe)(2)-H2O2 system, it is more stable and milder, affording broader application scopes due to a higher functional group tolerance. The control experiments for mechanism study disclosed that air was the key factor for the reaction to maintain enough concentration of PhSeOH, which should be the real catalytic species.

• 出版日期2015-12-4
• 单位扬州大学