In Vivo Characterization of Healthy Oral Mucosa by Reflectance Confocal Microscopy: A Translational Research for Optical Biopsy

作者：Contaldo Maria; Agozzino Marina; Moscarella Elvira; Esposito Salvatore; Serpico Rosario; Ardigo Marco^*

来源：Ultrastructural Pathology, 2013, 37(2): 151-158.

DOI：10.3109/01913123.2013.776656

• In vivo imaging
• oral mucosa
• reflectance confocal microscopy

Purpose: To characterize in vivo microscopic features of healthy oral mucosa by noninvasive, real-time reflectance confocal microscopy (RCM). %26lt;br%26gt;Material and Methods: One hundred healthy mucosal sites (38 lips, 24 cheeks, 10 gingivae, and 28 tongues) from 50 randomly selected volunteers were imaged by a commercially available in vivo RCM (Vivascope3000, Lucid, Rochester, NY). Morphological results were described and correlated with conventional histology. %26lt;br%26gt;Results: Specific microscopic parameters (cellular morphology, anatomical structures features, architectural patterns) were identified by RCM for each mucosal site. %26lt;br%26gt;Conclusions: RCM features reproducibility in different mucosal sites and subjects, which suggests that RCM can be an adjunct tool for clinical management in stomatology.

• 出版日期2013-4