Analysis of Consequences of Birth Asphyxia in Infants: A Regional Study in Southern Punjab, Pakistan

作者：Samad Noreen^*; Farooq Samia; Hafeez Kinza; Maryam Mukharma; Rafi Muhammad Aftab

来源：Journal of the College of Physicians and Surgeons Pakistan, 2016, 26(12): 950-953.

• LDH
• ALT
• AST
• Creatinine
• Bilirubin
• Urea
• Platelet count
• Birth asphyxia

Objective: To evaluate the biochemical consequences and platelet counts of birth asphyxia in neonates.
Study Design: Cohort study.
Place and Duration of Study: Department of Child Health, Nishter Medical College and Hospital, Multan, from September to November 2015.
Methodology: The data of 50 (50%) asphyxiated neonates and 50 (50%) non-asphyxiated neonates, with age range less than 1 month, was collected from Children Ward of Nishtar Hospital, Multan, Pakistan. Data on platelet count in blood, kidney function tests (creatinine, urea), liver function tests (bilirubin, alanine aminotransferase (ALT), aspartate aminotransferase (AST)) and cardiac enzyme test (lactate dehydrogenase (LDH)) were analysed by paired sample t-test by SPSS software. Sociodemographic data of those neonate's mothers was also collected.
Results: In asphyxiated neonates LDH, ALT, AST, creatinine, bilirubin, urea levels were higher than healthy infants, while the platelet count was smaller in asphyxiated neonates than healthy infants.
Conclusion: There was a higher rate of alteration in platelet count, levels of LDH, AST, ALT, urea creatinine and bilirubin in asphyxiated infants. These alterations may be correlated with damage of vital organ of asphyxiated neonates.

• 出版日期2016-12