Multiple Sclerosis on Steroids

作者：Johnson Matthew S; Lee Michael S^*; Younge Brian R; Purvin Valerie

来源：Survey of Ophthalmology, 2010, 55(5): 460-466.

DOI：10.1016/j.survophthal.2009.11.002

• bilateral visual loss
• fulminant
• Marburg
• multiple sclerosis
• optic neuritis
• treatment

A 57-year-old man developed acute bilateral vision loss clinically consistent with bilateral optic neuritis. Within 1 month of diagnosis, he developed progressive and severe neurologic dysfunction, and repeat MRI demonstrated enhancement of the optic chiasm and optic tracts, as well as a large enhancing lesion within the right parieto-occipital lobe. Stereotactic-guided brain biopsy demonstrated demyelination consistent with multiple sclerosis. A diagnosis of fulminant multiple sclerosis was made. The patient died within 2 months of diagnosis. Multiple sclerosis and a fulminant subtype known as Marburg disease are discussed. (Surv Ophthalmol 55:460-466, 2010.

• 出版日期2010-10