Abalone Viscera Protein Hydrolysate Modulation of Gut Microbiota in a Mouse Model of Alcohol induced Injury

作者：Wu, Jingna; Qiao, Kun; Lu, Haixia; Chen, Xiaoting; Su, Jie; Liu, Zhiyu^*

来源：Journal of Aquatic Food Product Technology, 2017, 26(7): 880-889.

DOI：10.1080/10498850.2017.1375586

• Abalone viscera protein hydrolysate
• gut microbiota
• illumina sequencing

In this study, the structural changes of gut microbiota in response to abalone viscera protein hydrolysate (AVPH) were examined in alcohol induced injured mice. The gut microbiota of mice without treatment (blank), alcohol treatment (control), and alcohol+AVPH treatment (sample) were profiled with Illumina sequencing of the V4 region of 16S rDNA genes. The sequencing results revealed that 705, 654, and 888 of Operational Taxonomic Units (OTUs) were determined in the blank, control, and sample groups, respectively. Compared with the control and blank groups, the AVPH had a higher diversity index and a larger number of reads subjecting to Bacilli (class), Lactobacillales (order), Lactobacillaceae (family), and Lactobacillus (genus) levels. However, insignificant difference of beta-diversity or principal component among control, blank, and sample groups was found. This study demonstrates that the in vivo oxidation inhibition pathway in alcohol induced injured mice by AVPH was not via modulating the gut microbiota structure.

• 出版日期2017
• 单位福建省水产研究所; 华侨大学