A Short and Efficient Synthesis of Licochalcone E

作者：Li Jizhen^*; Mi Yuhua; He Jianghua; Deng Xuming

来源：Synlett, 2010, (15): 2289-2292.

DOI：10.1055/s-0030-1258029

• licochalcone E
• abnormal Claisen rearrangement
• Claisen-Schmidt condensation
• total synthesis

Licochalcone E was synthesized concisely via an abnormal Claisen rearrangement and Claisen-Schmidt condensation as the key reactions in a three-step sequence. The overall yield is 20% starting from prenyl bromide and 4-hydroxy-2-methoxybenzaldehyde.

• 出版日期2010-9
• 单位吉林大学