Analysis of Instantaneous Linear, Nonlinear and Complex Cardiovascular Dynamics from Video-photoplethysmography

作者：Valenza Gaetano^*; Iozzia Luca; Cerina Luca; Mainardi Luca; Barbieri Riccardo

来源：Methods of Information in Medicine, 2018, 57(2): 135-140.

DOI：10.3414/ME17-02-0013

• Video-photoplethysmography
• heart rate variability
• point process
• nonlinear analysis
• complexity
• bispectrum
• sympatho-vagal balance
• ECG

Background: There is a fast growing interest in the use of non-contact devices for health and performance assessment in humans. In particular, the use of non-contact video-photoplethysmography (vPPG) has been recently demonstrated as a feasible way to extract cardiovascular information. Nevertheless, proper validation of vPPG-derived heartbeat dynamics is still missing.
Objective: We aim to an in-depth validation of time-varying, linear and nonlinear/complex dynamics of the pulse rate variability extracted from vPPG.
Methods: We apply inhomogeneous point-process nonlinear models to assess instantaneous measures defined in the time, frequency, and bispectral domains as estimated through vPPG and standard ECG. Instantaneous complexity measures, such as the instantaneous Lyapunov exponents and the recently defined inhomogeneous point-process approximate and sample entropy, were estimated as well. Video recordings were processed using our recently proposed method based on zero-phase principal component analysis. Experimental data were gathered from 60 young healthy subjects (age: 2 +/- 3 years) undergoing postural changes (rest-to-stand maneuver).
Results: Group averaged results show that there is an overall agreement between linear and nonlinear/complexity indices computed from ECG and vPPG during resting state conditions. However, important differences are found, particularly in the bispectral and complexity domains, in recordings where the subjects has been instructed to stand up.
Conclusions: Although significant differences exist between cardiovascular estimates from vPPG and ECG, it is very promising that instantaneous sympathovagal changes, as well as time-varying complex dynamics, were correctly identified, especially during resting state. In addition to a further improvement of the video signal quality, more research is advocated towards a more precise estimation of cardiovascular dynamics by a comprehensive nonlinear/complex paradigm specifically tailored to the non-contact quantification.

• 出版日期2018-5