The levels of zearalenone and its metabolites in plasma, urine and faeces of horses fed with naturally, Fusarium toxin-contaminated oats

作者：Songsermsakul P; Boehm J; Aurich C; Zentek J; Razzazi Fazeli E^*

来源：Journal of Animal Physiology and Animal Nutrition, 2013, 97(1): 155-161.

DOI：10.1111/j.1439-0396.2011.01253.x

• zearalenone
• metabolite
• plasma
• urine
• faeces
• horses

Concentration profile of zearalenone (ZON) and its metabolites in plasma, urine and faeces samples of horses fed with Fusarium toxincontaminated oats is described. In plasma, beta-zearalenol (beta-ZOL) was detected at high levels on day 10 of the study (3.216.24 mu g/l). beta-Zearalenol and alpha-zearalenol were the major metabolites in urine. Zearalenone, alpha-ZOL and beta-ZOL were predominantly found in faeces. Zearalanone could also be detected in urine (1.345.79 mu g/l) and faeces (1 mu g/kg). The degree of glucuronidation was established in all sample types, approximately 100% in urine and plasma. Low per cent of glucuronidation (415%) was found in faeces samples. The results indicate the main conversion of ZON into beta-ZOL in horse. This finding could explain why horse is not susceptible to ZON in comparison with swine which produce a-ZOL as a predominant metabolite.

• 出版日期2013-2