A new and facile tetrachlorosilane-promoted one-pot condensation for the synthesis of a novel series of tetracyclic 1,5-thiazepines

作者：Khatab Tamer K^*; El Bayouki Khairy A M; Basyouni Wahid M

来源：Tetrahedron Letters, 2014, 55(44): 6039-6041.

DOI：10.1016/j.tetlet.2014.09.006

• 1,5-Benzothiazepine
• Tetracyclic
• Tetrachlorosilane
• One-pot synthesis

A new and facile approach for the one-pot synthesis of a novel series of tetracyclic 1,5-thiazepines is described. The reaction occurs through cyclocondensation of fused cyclic ketones, aromatic aldehydes, and 2-aminothiophenol using tetrachlorosilane as a promoter in methylene chloride at ambient temperature.

• 出版日期2014-10-29