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摘要
The present study was undertaken to investigate the antioxidant, anticancer, and cytotoxic properties of 18 ethanol extracts of the plant-based preparations described in Thai Pharmaceutical Textbook and locally used as rejuvenators. 'Tri-Su-Ra-Phon', 'Tri-Sa-Mo', 'Jatu-PhaLa-Ti-Ga', and 'Nava-Kot' extracts had much higher antioxidant activities than those of standard trolox and ascorbic acid. The percentage inhibitions, using 2,2-diphenyl-1-picrylhydrazyl free radical (DPPH) and 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) methods, of these extracts were found to be approximately 73.33 +/- 6.01-93.50 +/- 0.30% and 73.71 +/- 2.77-101.86 +/- 0.54%, respectively. 'Tri-Su-Ra-Phon' extract presented the highest phenolic and flavonoid contents of 1373.40 mg gallic acid equivalent/g of extract and 4290.60 mg catechin equivalent/g of extract, respectively. Moreover, 'Jatu-Pha-La-Ti-Ga', 'Tri-Sa-Mo', and 'Tri-Su-Ra-Phon' exhibited significant anticancer activity against human breast cancer cell lines with selectivity indexes of 3-12. Based on this information, it could be concluded that 'Jatu-Pha-La-Ti-Ga', 'Tri-Sa-Mo', and 'Tri-Su-Ra-Phon' have great potential to be used in the development of functional beverages that are currently in demand for health benefits.
- 出版日期2015-2
