Measurement of NT-proBNP with LOCI (R) technology in heart failure patients

作者：Gruson D^*; Ahn Sylvie A; Lepoutre Thibault; Rousseau Michel F

来源：Clinical Biochemistry, 2012, 45(1-2): 171-174.

DOI：10.1016/j.clinbiochem.2011.07.012

• LOCI
• NT-proBNP
• Heart failure
• Severity

Objectives: The aim of our study was to determine NT-proBNP concentrations in heart failure (HF) patients with a luminescent oxygen channeling immunoassay (LOCI (R)). %26lt;br%26gt;Design and methods: Seventy HF patients were enrolled. NT-proBNP levels were measured with LOCI (R) method and compared to a reference NT-proBNP assay. %26lt;br%26gt;Results: LOCI (R) NT-proBNP levels were significantly correlated with the reference NT-proBNP assay and were related to HF severity. %26lt;br%26gt;Conclusions: LOCI (R) assay demonstrates performances close to the comparative assay for NT-proBNP testing and allows a significant reduction of the time of analysis.

• 出版日期2012-1